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Impact of indoor residual spraying with pirimiphos-methyl (Actellic 300CS) on entomological indicators of transmission and malaria case burden in Migori County, western Kenya

Bernard Abong’o, John E. Gimnig, Stephen J. Torr, Bradley Longman, Diana Omoke, Margaret Muchoki, Feiko ter Kuile, Eric Ochomo, Stephen Munga, Aaron M. Samuels, Kiambo Njagi, James Maas, Robert T. Perry, Christen Fornadel, Martin J. Donnelly & Richard M. Oxborough


March 24, 2020

A U.S. President's Malaria Initiative VectorLink Project study in western Kenya shows one round of indoor residual spraying (IRS) with pirimiphos-methyl is highly effectively at providing year-round protection against the indoor biting and resting pyrethroid-resistant An. funestus mosquitoes. The spraying reduced the number of mosquitoes and malaria cases. The study found less impact on An. arabiensis, likely due to its outdoor-biting and resting behavior. That vector requires additional control measures. The study appears in the peer-reviewed Scientific Reports, the 11th most cited journal in the world.